База результатов деятельности
научных работников ФИЦ ИнБЮМ
Научно-информационный отдел ФИЦ ИнБЮМ
+7 8692 54-55-50
sci-info@ibss-ras.ru

Дата внесения публикации в базу 22-11-2022 11:37 не попадает в период стимулирования 01-06-2023 – 31-05-2024
Количество соавторов публикации - 5
Публикация не попадает под расчет КБПР
  • Геворгиз Р. Г.: количество аффилиаций - 1, вклад в КБПР публикации:
    формула: K/(Nсоавторов*Nаффил) = 0/(5*1) = 0
  • Железнова С. Н.: количество аффилиаций - 1, вклад в КБПР публикации:
    формула: K/(Nсоавторов*Nаффил) = 0/(5*1) = 0
Материалы конференции

The Influence of Fucoxanthin Immobilized on Porous Aluminum-Silicon Carrier Surface on the Functional Activities of Immunocytes in Mice

DOI https://doi.org/10.18502/kls.v7i1.10109
Язык Английский
Конференция
Место проведения:
Даты проведения:
Год публикации 2022
Сборник 8th Scientific and Practical Conference "Biotechnology: Science and Practice", Yalta, 22-26 Sept., 2020 : [conf. papers]
Выходные данные [Yalta], 2022. P. 77-83. (KnE Life Sciences)
Авторы
  1. Lykov A.
    Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics SB RAS, Novosibirsk, Russian Federation (ru)
  2. Rachkovskaya L.
    Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics SB RAS, Novosibirsk, Russian Federation (ru)
  3. Геворгиз Р. Г. (Gevorgiz R.)
  4. Железнова С. Н. (Zheleznova S.)
  5. Poveshchenko O.
    Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics SB RAS, Novosibirsk, Russian Federation (ru)
Абстракт Fucoxanthin is a natural carotenoid obtained from seaweed which exhibits antioxidant properties. This research aimed to assess whether fucoxanthin, immobilized on aluminum-silicon carrier particles, has a toxic effect on immune cells. The viability, proliferation, nitric oxide production and myeloperoxidase activity of thymocytes and splenocytes of mice in vitro were studied. It was shown that fucoxanthin, immobilized on aluminum-silicon carrier particles, increased the survival rate and proliferation of mature immunocytes (splenocytes) after 24 hours exposure and increased the survival rate of naïve immunocytes (thymocytes) when exposed for 120 hours. In terms of myeloperoxidase, the activity of the immune cells was not affected by fucoxanthin immobilized on the carrier particles. The obtained results indicated that fucoxanthin, immobilized on particles of an aluminum-silicon carrier, did not have a toxic effect on mouse immunocytes.
Ключевые слова: Cylindrotheca closterium, fucoxanthin, γ-aluminum oxide, polydimethylsiloxane, thymocytes, splenocytes, viability, proliferation, nitric oxide, myeloperoxidase activity
Сведения о финансировании, указанные в публикации
URL https://knepublishing.com/index.php/KnE-Life/article/view/10109
Дополнительные сведения

Запись создана: 22-11-2022 11:37
Последнее изменение: 22-11-2022 11:39

Библиографическая ссылка:
Lykov A., Rachkovskaya L., Gevorgiz R., Zheleznova S., Poveshchenko O. The Influence of Fucoxanthin Immobilized on Porous Aluminum-Silicon Carrier Surface on the Functional Activities of Immunocytes in Mice // 8th Scientific and Practical Conference "Biotechnology: Science and Practice", Yalta, 22-26 Sept., 2020 : [conf. papers]. [Yalta], 2022. P. 77-83. (KnE Life Sciences). https://doi.org/10.18502/kls.v7i1.10109
Экспертное заключение: –
Индексация на момент включения в базу:
Web of Science
Статус
Нет
SCOPUS
Статус
Нет
РИНЦ
Статус
Нет
ID
EDN