Bioavailability and Safety of Lipid Fraction from Different Taxa of Microalgae in Female C57BL/6 Mice

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Дата внесения публикации в базу 23-11-2021 10:17 не попадает в период стимулирования 01-06-2023 – 31-05-2024

КБПР (данная функция работает в тестовом режиме) 0.25

Количество соавторов публикации - 8
Публикации в изданиях, индексируемых в Web of Science Core Collection: без квартиля, K=1

Геворгиз Р. Г.: количество аффилиаций - 1, вклад в КБПР публикации:
формула: K/(Nсоавторов*Nаффил) = 1/(8*1) = 0.125

Железнова С. Н.: количество аффилиаций - 1, вклад в КБПР публикации:
формула: K/(Nсоавторов*Nаффил) = 1/(8*1) = 0.125

Статья в периодическом издании

Bioavailability and Safety of Lipid Fraction from Different Taxa of Microalgae in Female C57BL/6 Mice

WoS –/– SCOPUS 0.216/Q4

DOI	https://doi.org/10.33263/BRIAC125.68456862
Язык	Английский
Журнал	Biointerface Research in Applied Chemistry ISSN: —; Онлайн ISSN: 2069-5837
Год	2022
Выходные данные	Том: 12, Выпуск: 5, Страницы: 6845-6862
Авторы	Lykov A. Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia (ru) Research Center, Ministry of Health of the Russian Federation, Novosibirsk, Russia (ru) Federal State Budgetary Institution "Novosibirsk Tuberculosis Research Institute", Ministry of Health of the Russian Federation/ Novosibirsk, Russia (ru) Uvarov I. State Budgetary Institution of the Novosibirsk Region "Department of Veterinary Medicine of the City Novosibirsk", Novosibirsk, Russia (ru) Геворгиз Р. Г. (Gevorgiz R.) Железнова С. Н. (Zheleznova S.) Surovtseva M. Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia (ru) Research Center, Ministry of Health of the Russian Federation, Novosibirsk, Russia (ru) Kim I. Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia (ru) Research Center, Ministry of Health of the Russian Federation, Novosibirsk, Russia (ru) Bondarenko N. Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia (ru) Research Center, Ministry of Health of the Russian Federation, Novosibirsk, Russia (ru) Poveshchenko O. Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia (ru) Research Center, Ministry of Health of the Russian Federation, Novosibirsk, Russia (ru)
Даты	Поступила в редакцию: 04.09.2021 После доработки 14.10.2021 Опубликована онлайн: 18.10.2021 Опубликована: 20.11.2021
Абстракт	Microalgae exhibit antioxidant, anti-inflammatory effects. In this study, we analyzed the toxicity of lipid fraction of different taxa of microalgae in female C57BL/6 mice. The number of red blood cells, white blood cells and subsets, hemoglobin, number, and functional activities of immature and mature immunocytes, biochemical parameters in blood serum, and kidney and liver extract were investigated. It is shown that the lipid fraction of microalgae had no acute toxic effect on body weight, glucose blood levels, and hemopoiesis in mice. Some changes in the number of immature and mature lymphocytes, proliferative potential, Ig levels, cytokine production were determined. In vivo lipid fraction of microalgae caused changes in cytokine, protein, lipid, purine, aminotransferases, and sex hormone level in mice. Obtained data indicate that lipid fraction dietary administration in female C57BL/6 mice does not have a toxic effect on the animal. Ключевые слова: lipid fraction of microalgae, Chlorella vulgaris, Coelastrella sp., Spirulina platensis, Cylindrotheca closterium, Porphyridium purpureum, immature and mature lymphocytes, hematopoiesis, proliferation, cytokine, protein and lipid status, aminotransferase activit, sex hormone
Сведения о финансировании, указанные в публикации	This research was carried out within the framework of government research assignment of RICEL-branch of ICG RAS "Development of methods of molecular profiling and innovative technologies for prediction, early diagnosis, drug and cell therapy of socially significant human diseases of autoimmune, inflammatory and dysmetabolic nature" No. АААА-А19- 119031590016-0 and IBSS RAS "Investigation of the mechanisms of controlling production processes in biotechnological complexes with the aim of developing the scientific foundations for the production of biologically active substances and technical products of marine genesis" No. АААА-А18-118021350003-6.
URL	https://biointerfaceresearch.com/wp-content/uploads/2021/11/20695837125.69606977.pdf
Дополнительные сведения

Запись создана: 23-11-2021 10:17
Последнее изменение: 27-02-2023 11:17

Страница журнала в E-library

Библиографическая ссылка:
Lykov A., Uvarov I., Gevorgiz R., Zheleznova S., Surovtseva M., Kim I., Bondarenko N., Poveshchenko O. Bioavailability and Safety of Lipid Fraction from Different Taxa of Microalgae in Female C57BL/6 Mice // Biointerface Research in Applied Chemistry. 2022. Vol. 12, iss. 5. P. 6845-6862. https://doi.org/10.33263/BRIAC125.68456862
[WoS –/–][SCOPUS 0.216/Q4]

Экспертное заключение: № 387, 2021

Индексация на момент включения в базу:
Web of Science

Статус: Да
Импакт-фактор/Квартиль(год): –/– (–)
Идентификатор: 000721362000020

SCOPUS

Статус: Да
Импакт-фактор/Квартиль(год): 0.216/Q4 (2020)
Идентификатор: 2-s2.0-85119378666

РИНЦ

Статус: Нет
ID: 47530233
EDN: HAEVZL

В публикации указано госзадание:

№ 121030300149-0 «Исследование механизмов управления продукционными процессами в биотехнологических комплексах с целью разработки научных основ получения биологически активных веществ и технических продуктов морского генезиса» (предыдущий номер АААА-А18-118021350003-6)

Тэги:

ЦКП Коллекция гидробионтов Мирового океана