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Дата внесения публикации в базу 29-09-2020 10:49 не попадает в период стимулирования 01-06-2023 – 31-05-2024
Количество соавторов публикации - 11
Публикации в изданиях, индексируемых в Web of Science Core Collection: без квартиля, K=1
  • Геворгиз Р. Г.: количество аффилиаций - 1, вклад в КБПР публикации:
    формула: K/(Nсоавторов*Nаффил) = 1/(11*1) = 0.091
  • Железнова С. Н.: количество аффилиаций - 1, вклад в КБПР публикации:
    формула: K/(Nсоавторов*Nаффил) = 1/(11*1) = 0.091
Статья в периодическом издании

In Vitro and In Vivo Effect of the Composition of Fucoxanthin with Porous Aluminum-Silicon Career on Cells

WoS –/– SCOPUS 0.161/Q4
DOI https://doi.org/10.33263/BRIAC112.94679476
Язык Английский
Журнал Biointerface Research in Applied Chemistry

ISSN: —; Онлайн ISSN: 2069-5837
Год 2021
Выходные данные Том: 11, Выпуск: 2, Страницы: 9467-9476
Авторы
  1. Lykov A.
    Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russi (ru)
  2. Rachkovskaya L.
    Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia (ru)
  3. Surovtseva M.
    Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia (ru)
  4. Kim I.
    Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia (ru)
  5. Rachkovsky E.
    Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia (ru)
  6. Геворгиз Р. Г. (Gevorgiz R.)
  7. Железнова С. Н. (Zheleznova S.)
  8. Korolev M.
    Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia (ru)
  9. Kotlyarova A.
    Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia (ru)
  10. Letyagin A.
    Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia (ru)
  11. Poveshchenko O.
    Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia (ru)
Даты Поступила в редакцию: 19.08.2020
После доработки 09.09.2020
Принята к публикации: 10.09.2020
Опубликована: 13.09.2020
Абстракт Fucoxanthin natural carotenoid from seaweeds exhibits antioxidant properties. The paper analyzes the possibility of using fucoxanthin, immobilized on aluminum-silicon carrier particles, to assess the toxic effect on naïve or matured immune cells, enterocytes, Mesenchymal stem cells, and EA.Hy926 cell line. The proliferation, nitric oxide production, myeloperoxidase activity, and apoptosis of thymocytes and splenocytes of mice in vitro were studied. Proliferative capacity, nitric oxide production, and apoptosis rate of entreocytes, mesenchymal stem cells and EA.Hy926 cell line were investigated. It is shown that fucoxanthin immobilized on aluminum-silicon carrier particles increased the survival rate and proliferation of mature immunocytes (splenocytes) after 24 hours exposure and increased the survival rate of naïve immunocytes (thymocytes) when exposed 120 hours. On myeloperoxidase, the activity of immune cells is not affected by fucoxanthin immobilized on the carrier particles. Orally the administration of some samples of fucoxanthin immobilized on the carrier particles with different sizes, and dosage no have an adverse effect on jejunum enterocytes (proliferation and apoptosis). In vitro, all tested samples of fucoxanthin immobilized on the carrier particles with different sizes and dosage in common no have a toxic effect on jejunum enterocytes, human bone marrow mesenchymal stem cells, and EA.Hy926 cell line. The obtained results indicate that fucoxanthin, immobilized on particles of an aluminum-silicon carrier, does not have a toxic effect on mouse immunocytes and enterocytes, and human mesenchymal stem cells and EA.Hy92 cell line.
Ключевые слова: Cylindrotheca closterium, fucoxanthin, γ-aluminum oxide, polydimethylsiloxane, immunocytes, enterocytes, mesenchymal stem cells, EA.Hy926
Сведения о финансировании, указанные в публикации
URL https://biointerfaceresearch.com/wp-content/uploads/2020/09/20695837112.94679476.pdf
Дополнительные сведения

Запись создана: 29-09-2020 10:49
Последнее изменение: 03-12-2021 16:15

Страница журнала в E-library
Библиографическая ссылка:
Lykov A., Rachkovskaya L., Surovtseva M., Kim I., Rachkovsky E., Gevorgiz R., Zheleznova S., Korolev M., Kotlyarova A., Letyagin A., Poveshchenko O. In Vitro and In Vivo Effect of the Composition of Fucoxanthin with Porous Aluminum-Silicon Career on Cells // Biointerface Research in Applied Chemistry. 2021. Vol. 11, iss. 2, P. 9467-9476. https://doi.org/10.33263/BRIAC112.94679476
[WoS –/–][SCOPUS 0.161/Q4]
Экспертное заключение: № 329, 2020
Индексация на момент включения в базу:
Web of Science
Статус
Да
Импакт-фактор/Квартиль(год)
–/– (–)
Идентификатор
000570975300073
SCOPUS
Статус
Да
Импакт-фактор/Квартиль(год)
0.161/Q4 (2019)
Идентификатор
2-s2.0-85090988067
РИНЦ
Статус
Нет
ID
45323726
EDN
–

В публикации указано госзадание:

№ 121030300149-0 «Исследование механизмов управления продукционными процессами в биотехнологических комплексах с целью разработки научных основ получения биологически активных веществ и технических продуктов морского генезиса» (предыдущий номер АААА-А18-118021350003-6)

Тэги:
ЦКП Коллекция гидробионтов Мирового океана